Fenben cancer treatment is becoming more popular as research continues to reveal the benefits of this anti-parasitic medication. Fenbendazole was originally developed to kill parasitic worms and deworm animals, but it is now known to effectively fight cancer cells as well. Several studies have shown that tumors do not grow in mice if fed with a diet that contains fenbendazole and vitamins. These experiments also show that fenbendazole inhibits cancer cell growth by targeting microtubules and inducing p53 to a higher level.
One of these studies was performed by a group of scientists that was trying to figure out why their lab mice were not getting lymphoma. These researchers gave the mice a diet that contained fenbendazole and lots of extra vitamins to see if it could prevent lymphoma development. The mice were supposed to be fed a normal diet, but the facility did not have the capability to autoclave or sterilize food, so extra vitamins were added to it instead.
In this study, they found that fenbendazole (FZ) caused glucose uptake inhibition and impairs hexokinase II (HK II) enzymatic activity in human NSCLC H460 cells. They also found that fenbendazole reduced cell-cycle progression, mitotic catastrophe, and apoptosis by targeting tubulin.
Fenbendazole is a moderate microtubule targeting agent that causes apoptosis in cancer cells. It does so by inducing p53 to a high level, inhibiting the mitotic spindle checkpoint, and interfering with the glucose metabolism. These results suggest that these mechanisms are collectively responsible for the preferential elimination of cancer cells by FZ. fenben cancer treatment
